Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MC3R | P41968 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094934 | 0.91 | POLB (0.56) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5430063 | 0.87 | POLB (0.46) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5086740 | 0.85 | GAA (0.50) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5088874 | 0.84 | GAA (0.49) | POLBAPEX1TDP1GAAKDM4E | |
| Phosphoric Acid SCHEMBL5430756 | 0.80 | GAA (0.45) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5094928 | 0.79 | GAA (0.53) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5162643 | 0.77 | CYP1A2 (0.45) | POLBAPEX1TDP1CYP1A2CYP3A4 | |
| SCHEMBL5482008 | 0.75 | SKP2 (0.58) | POLBGAAKDM4EMEN1MAPT | |
| SCHEMBL5086794 | 0.75 | GAA (0.49) | POLBAPEX1TDP1GAAKDM4E | |
| SCHEMBL5088894 | 0.74 | TRPV1 (0.68) | POLBGAAKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008510738-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | claimed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | claimed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | disclosed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | KRT18, TYR, ALPG | POLB 1283/4885APEX1 2354/4885TDP1 3603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.