Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | IARS1 | P41252 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.45 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5090335 | 0.92 | CA2 (0.57) | CA2L3MBTL1KDM4EGLAIARS1 | |
| SCHEMBL5089884 | 0.84 | TRPV1 (0.59) | CA2KDM4EIARS1TRPV1GAA | |
| SCHEMBL5094905 | 0.84 | CA2 (0.48) | CA2L3MBTL1KDM4EGLAIARS1 | |
| SCHEMBL5095795 | 0.82 | TRPV1 (0.50) | CA2KDM4EIARS1TRPV1GAA | |
| SCHEMBL5086765 | 0.82 | TRPV1 (0.50) | CA2KDM4EIARS1TRPV1GAA | |
| Phosphoric Acid SCHEMBL5434016 | 0.82 | TRPV1 (0.54) | CA2KDM4EIARS1TRPV1GAA | |
| SCHEMBL5088894 | 0.82 | TRPV1 (0.68) | CA2L3MBTL1KDM4EIARS1TRPV1 | |
| SCHEMBL5088853 | 0.81 | TRPV1 (0.51) | CA2KDM4EIARS1TRPV1GAA | |
| SCHEMBL5089854 | 0.80 | TRPV1 (0.55) | CA2KDM4ETRPV1GAACA1 | |
| SCHEMBL5094903 | 0.80 | TRPV1 (0.55) | CA2KDM4ETRPV1GAACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008510738-A | — | — | 2008-04-10 | — | — | JP | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | claimed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | claimed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | claimed |
| EP-1781597-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-05-09 | — | — | EP | disclosed |
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | THE PROCTER & GAMBLE COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2006021256-A1 | O-AMINOPHENOL DERIVATIVES AND DYES CONTAINING THESE COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099959-A1 | O-Aminophenol derivatives and colorants containing these compounds | KRT18, TYR, ALPG | CA2 1981/4885L3MBTL1 4401/4885KDM4E 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.