SCHEMBL5087254

SCHEMBL5087254

O=C1C(Br)=Cc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.64
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
MAPK1 P28482 3/20 0.64
PTPRC P08575 6/20 0.50
CDC25B P30305 3/20 0.48
CDC25A P30304 1/20 0.48
POLB P06746 3/20 0.46
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
BCHE P06276 2/20 0.46
THRB P10828 2/20 0.46
CES1 P23141 2/20 0.46
RECQL P46063 2/20 0.46
PTPN1 P18031 2/20 0.46
IDO1 P14902 2/20 0.46
HPGD P15428 2/20 0.46
PTPN22 Q9Y2R2 2/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29650595 0.93 MEN1 (0.57) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL4337875 0.93 MEN1 (0.57) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL826206 0.79
SCHEMBL16225115 0.79 MEN1 (1.00) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL30184802 0.79 MEN1 (1.00) MAPTMEN1KMT2AMAPK1PTPRC
2-Bromo-1,4-Naphthoquinone SCHEMBL312893 0.76 PTPRC (0.68) MAPTMEN1KMT2AMAPK1PTPRC
2-Bromo-1,4-Naphthoquinone SCHEMBL29633250 0.76 PTPRC (0.68) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL3444897 0.75 CDC25B (0.57) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL2971465 0.75 MAPK1 (0.42) MAPTMEN1KMT2AMAPK1PTPRC
SCHEMBL28493517 0.74 MEN1 (0.43) MAPTMEN1KMT2AMAPK1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116065410-B Water-less dyeing process for polyester-cotton blended fabric 浙江红利集团有限公司 2025-02-18 CN claimed
CN-114671829-B Heterodiad taking indenone and dibenzoazepine as parent nucleus and hydrochloride thereof, preparation method and application thereof 合肥工业大学 2023-07-25 CN claimed
CN-116065410-A Water-less dyeing process for polyester-cotton blended fabric 浙江红利集团有限公司 2023-05-05 CN claimed
WO-2008037604-A1 NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF UNIVERSITÀ DEGLI STUDI DI SIENA (IT) 2008-04-03 WO claimed
CN-119678263-A Slurry composition for negative electrode of secondary battery 三菱铅笔株式会社 2025-03-21 CN disclosed
CN-116065410-B Water-less dyeing process for polyester-cotton blended fabric 浙江红利集团有限公司 2025-02-18 CN disclosed
US-11912693-B2 Compounds for modulating S1P1 activity and methods of using the same TREVENA, INC. (US) 2024-02-27 US disclosed
CN-115895627-B Sulfur-resistant corrosion inhibitor and preparation method thereof 河南中原石油助剂有限公司 2023-10-31 CN disclosed
US-20230234946-A1 COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME TREVENA, INC. 2023-07-27 US disclosed
CN-114671829-B Heterodiad taking indenone and dibenzoazepine as parent nucleus and hydrochloride thereof, preparation method and application thereof 合肥工业大学 2023-07-25 CN disclosed
CN-116282078-A Salt recovery solution and method of using the same 阿克福特斯技术有限公司 2023-06-23 CN disclosed
CN-116065410-A Water-less dyeing process for polyester-cotton blended fabric 浙江红利集团有限公司 2023-05-05 CN disclosed
EP-0871612-B1 FUSED ISOINDOLONES AS INHIBITORS OF PROTEIN KINASE C CEPHALON INC (US) 2003-03-12 EP disclosed
EP-0885229-B1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON INC (US) 2000-08-02 EP disclosed
EP-0885229-A1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON, INC. (US) 1998-12-23 EP disclosed
US-5808060-A Fused isoindolones CEPHALON, INC. (US) 1998-09-15 US disclosed
US-5801190-A Fused pyrrolo 2,3-C! carbazole-6-ones CEPHALON, INC. (US) 1998-09-01 US disclosed
WO-1997031002-A1 FUSED PYRROLO(2,3-C)CARBAZOLE-6-ONES WHICH POTENTIATE ACTIVITY OF GAMMA INTERFERON CEPHALON, INC. (US) 1997-08-28 WO disclosed
US-5616724-A FOR POTENTIATION OF HUMAN INTERFERON-GAMMA; IMMUNOLOGY CEPHALON, INC. (US) 1997-04-01 US disclosed
CN-1087635-A Novel thiazole derivative, its preparation method and medical composition thereof YAMANOUCHI PHARMA CO LTD (JP) 1994-06-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234946-A1 COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME S1PR1, S1PR2, S1PR3 MAPT 3799/4885MEN1 645/4885KMT2A 2682/4885
US-11912693-B2 Compounds for modulating S1P1 activity and methods of using the same S1PR1, S1PR2, S1PR3 MAPT 3799/4885MEN1 645/4885KMT2A 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.