2-Bromo-1,4-Naphthoquinone

2-Bromo-1,4-Naphthoquinone

SCHEMBL312893

O=C1C=C(Br)C(=O)c2ccccc21

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 4/20 0.68
BACE1 P56817 2/20 0.57
CDC25B P30305 5/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
MAPT P10636 4/20 0.56
MAPK1 P28482 4/20 0.56
MAOA P21397 4/20 0.56
IDO1 P14902 3/20 0.56
LMNA P02545 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
MAOB P27338 3/20 0.56
CDC25A P30304 2/20 0.56
PLIN1 O60240 2/20 0.56
BLM P54132 2/20 0.56
PLIN5 Q00G26 2/20 0.56
ABHD5 Q8WTS1 2/20 0.56
ALDH1A1 P00352 2/20 0.56
SNCA P37840 2/20 0.56
NR1I2 O75469 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Bromo-1,4-Naphthoquinone SCHEMBL29633250 1.00 PTPRC (0.68) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL6345958 0.85 PTPRC (0.74) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL30412470 0.81 PTPRC (1.00) PTPRCCDC25BMEN1KMT2AMAPT
SCHEMBL6234343 0.81 PTPRC (1.00) PTPRCCDC25BMEN1KMT2AMAPT
SCHEMBL14566974 0.79 GAPDH (0.49) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL5087254 0.76 MAPT (0.64) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL28845752 0.76 S100A4 (0.61) PTPRCMEN1KMT2AMAPTMAPK1
SCHEMBL6555840 0.75 BACE1 (0.75) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL4657279 0.73 MAPT (0.58) PTPRCBACE1CDC25BMEN1KMT2A
SCHEMBL29673492 0.73 BACE1 (1.00) PTPRCBACE1CDC25BMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042935-A1 PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION NOVO NORDISK A/S (DK) 2025-02-06 US claimed
CN-118948532-A Preparation method of protection pad with function of early warning of abnormal pH value of vaginal secretion 上海焕了个新智能科技有限公司 2024-11-15 CN claimed
EP-4444735-A1 PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION Novo Nordisk A/S (DK) 2024-10-16 EP claimed
WO-2023105074-A1 PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION NOVO NORDISK A/S (DK) 2023-06-15 WO claimed
CN-115305245-A Preparation method of small molecule compound and novel coronavirus main protease protein cocrystal 山东达因海洋生物制药股份有限公司 2022-11-08 CN claimed
CN-114563494-A Method for detecting halogenated naphthoquinone in drinking water by solid phase extraction, vacuum centrifugal concentration and liquid chromatography tandem mass spectrometry 浙江大学 2022-05-31 CN claimed
CN-113461506-A Preparation process of 2-bromo-1, 4-naphthoquinone 苏州求索生物科技有限公司 2021-10-01 CN claimed
CN-108069845-B One-step preparation method of bromo-1, 4-naphthoquinone 大连理工大学 2020-04-14 CN claimed
WO-2018219574-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS HENKEL AG & CO. KGAA (DE) 2018-12-06 WO claimed
EP-3409707-A1 METHOD FOR PRODUCING FUNCTIONALIZED POLYESTERS Henkel AG & Co. KGaA (DE) 2018-12-05 EP claimed
CN-105308785-A Flow battery based on organic micromolecules HARVARD COLLEGE 2016-02-03 CN claimed
EP-2859068-A1 METHODS FOR SUPPRESSING DEHYDROGENATION Elevance Renewable Sciences, Inc. (US) 2015-04-15 EP claimed
WO-2013188200-A1 METHODS FOR SUPPRESSING DEHYDROGENATION ELEVANCE RENEWABLE SCIENCES, INC. (US) 2013-12-19 WO claimed
WO-2013188201-A1 METHODS OF REFINING NATURAL OILS, AND METHODS OF PRODUCING FUEL COMPOSITIONS ELEVANCE RENEWABLE SCIENCES, INC. (US) 2013-12-19 WO claimed
US-20130331586-A1 METHODS OF REFINING NATURAL OILS, AND METHODS OF PRODUCING FUEL COMPOSITIONS ELEVANCE RENEWABLE SCIENCES, INC. 2013-12-12 US claimed
US-20130331630-A1 METHODS FOR SUPPRESSING DEHYDROGENATION ELEVANCE RENEWABLE SCIENCES, INC. 2013-12-12 US claimed
CN-100573999-C Nonaqueous electrolytic solution and the lithium secondary battery that comprises it SAMSUNG SDI CO LTD (KR) 2009-12-23 CN claimed
CN-1531134-A Non-aqueous cell liquor and lithium secondary battery containing it 三星SDI株式会社 2004-09-22 CN claimed
EP-0436921-B1 Inhibitor concentrate, storage stable unsaturated thermosettable resins and cured products DOW CHEMICAL CO (US) 1997-03-12 EP claimed
US-4220528-A CONTACTING A GAS WITH A SOLUTION CONTAINING A HYDRAZINE, A QUINONE, AN ALKALI; CONTACTING THE DEOXYGENATED GAS WITH WATER OTSUKA CHEMICAL CO., LTD. (JP) 1980-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042935-A1 PHOTOCHEMICAL APPROACH TO C-TERMINAL A-AMIDATION IAPP, PTMS, VIP PTPRC 2967/4885BACE1 76/4885CDC25B 1289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.