Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5093193 | 0.80 | METAP1 (0.39) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL3420297 | 0.79 | METAP1 (0.45) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL5379959 | 0.79 | METAP1 (0.41) | METAP1CA12CA1CA2MMP2 | |
| Hydrochloric Acid SCHEMBL5372878 | 0.77 | METAP1 (0.44) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL14559784 | 0.75 | CYP1A2 (0.48) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL14559785 | 0.75 | CYP1A2 (0.48) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL10901117 | 0.74 | MMP2 (0.41) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL8732595 | 0.71 | MMP2 (0.48) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL2331815 | 0.71 | METAP1 (0.50) | METAP1CA12CA1CA2MMP2 | |
| SCHEMBL5509358 | 0.69 | CA12 (0.39) | METAP1CA12CA1CA2MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033572-A1 | ACYLOXYALKYL CARBAMATE PRODRUGS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-03-20 | — | — | WO | disclosed |