SCHEMBL508741

SCHEMBL508741

CCOC(=O)N[C@H](C=O)Cc1cnc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 16/20 0.49
HRH4 Q9H3N8 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863500 0.88 CYP3A4 (0.46) HRH3HRH4
Hydrochloric Acid SCHEMBL27702031 0.80 ITGB2 (0.60) HRH3HRH4
SCHEMBL13550920 0.79 CYP3A4 (0.47) HRH3HRH4
SCHEMBL11614717 0.79 HRH3 (0.48) HRH3HRH4
SCHEMBL11117873 0.76 HRH3 (0.47) HRH3HRH4
SCHEMBL17119231 0.76 HRH3 (0.47) HRH3HRH4
SCHEMBL9751643 0.76 HRH3 (0.50) HRH3HRH4
SCHEMBL17119227 0.76 HRH3 (0.50) HRH3HRH4
SCHEMBL16767779 0.76 SLC15A2 (0.48)
SCHEMBL10795770 0.75 ITGB2 (0.46) HRH3HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1266013-B1 HEPARINASE III AND USES THEREOF MASSACHUSETTS INST TECHNOLOGY (US) 2014-10-15 EP disclosed
US-8748193-B2 Apparatus for desorption and ionization of analytes BAYLOR COLLEGE OF MEDICINE (US) 2014-06-10 US disclosed
US-20120027744-A1 MODIFIED HEPARINASE III AND METHODS OF SEQUENCING THEREWITH MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2012-02-02 US disclosed
US-7939292-B2 Modified heparinase III and methods of sequencing therewith MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-05-10 US disclosed
US-20090256069-A1 APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES BAYLOR COLLEGE OF MEDICINE (US) 2009-10-15 US disclosed
US-20090081635-A1 MODIFIED HEPARINASE III AND METHODS OF SEQUENCING THEREWITH MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2009-03-26 US disclosed
US-7491549-B2 Apparatus for desorption and ionization of analytes BAYLOR COLLEGE OF MEDICINE (US) 2009-02-17 US disclosed
US-7455986-B2 Heparinase III and methods of specifically cleaving therewith MASSACHUSETTS INSTITUTE OF TECHNOLOGY, INC. (US) 2008-11-25 US disclosed
US-7413909-B2 Method and apparatus for desorption and ionization of analytes BAYLOR COLLEGE OF MEDICINE (US) 2008-08-19 US disclosed
US-7390633-B2 Methods for preparing low molecular weight heparin with modified heparinase III MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-06-24 US disclosed
EP-1266013-A2 HEPARINASE III AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-12-18 EP disclosed
US-20020122793-A1 Heparinase III and uses thereof NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-05 US disclosed
US-20020037517-A1 Methods for sequencing biopolymers HUTCHENS WILLIAM T (US) 2002-03-28 US disclosed
WO-2001066772-A2 HEPARINASE III AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-09-13 WO disclosed
US-6124137-A APPARATUS FOR DETECTING AN ANALYTE IMMOBILIZED TO A SURFACE; FOR RECEPTIVITY DIRECTED DETECTION OF BIOPLOYMERS; FOR SEQUENCING BIOPOLYMERS BAYLOR COLLEGE OF MEDICINE (US) 2000-09-26 US disclosed
US-6020208-A Systems for surface-enhanced affinity capture for desorption and detection of analytes BAYLOR COLLEGE OF MEDICINE (US) 2000-02-01 US disclosed
US-5719060-A Method and apparatus for desorption and ionization of analytes BAYLOR COLLEGE OF MEDICINE (US) 1998-02-17 US disclosed
EP-0700521-A4 METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES BAYLOR COLLEGE MEDICINE (US) 1997-06-11 EP disclosed
EP-0700521-A1 METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES BAYLOR COLLEGE OF MEDICINE (US) 1996-03-13 EP disclosed
WO-1994028418-A1 METHOD AND APPARATUS FOR DESORPTION AND IONIZATION OF ANALYTES BAYLOR COLLEGE OF MEDICINE (US) 1994-12-08 WO disclosed