Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.41 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751643 | 1.00 | HRH3 (0.50) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL17119231 | 0.84 | HRH3 (0.47) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL11117873 | 0.84 | HRH3 (0.47) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL29312929 | 0.83 | HRH4 (0.46) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL14213359 | 0.83 | HRH4 (0.50) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL13550919 | 0.81 | HRH4 (0.45) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL12735917 | 0.81 | HRH4 (0.47) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL13863500 | 0.79 | CYP3A4 (0.46) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL16557054 | 0.78 | HRH4 (0.41) | HRH3HRH4ALDH1A1MEN1KMT2A | |
| SCHEMBL24855254 | 0.78 | CYP3A4 (0.48) | HRH3HRH4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254919-A1 | SELECTIVE TMPRSS2 INHIBITORS AND MEDICAL USE THEREOF | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2021-12-23 | — | — | WO | disclosed |
| US-20150265732-A1 | GRPR-ANTAGONISTS FOR DETECTION, DIAGNOSIS AND TREATMENT OF GRPR-POSITIVE CANCER | ADVANCED ACCELERATOR APPLICATIONS INTERNATIONAL SA (CH) | 2015-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150265732-A1 | GRPR-ANTAGONISTS FOR DETECTION, DIAGNOSIS AND TREATMENT OF GRPR-POSITIVE CANCER | GRPR, GIPR, CCKBR | HRH3 189/4885HRH4 178/4885ALDH1A1 4001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.