⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720348 | 0.75 | — | — | |
| SCHEMBL42164 | 0.75 | — | — | |
| SCHEMBL19381 | 0.75 | — | — | |
| SCHEMBL9183026 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL83729 | 0.71 | — | — | |
| SCHEMBL392874 | 0.71 | — | — | |
| SCHEMBL2456516 | 0.69 | — | — | |
| SCHEMBL4466461 | 0.69 | — | — | |
| SCHEMBL11022588 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL2457037 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-114685505-A | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-110312719-B | Imidazopyrrolopyridines as JAK family kinase inhibitors | 詹森药业有限公司 | 2022-04-15 | — | — | CN | disclosed |
| US-11203573-B2 | N-alkylation of acridans | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2021-12-21 | — | — | US | disclosed |
| US-20210230119-A1 | N-ALKYLATION OF ACRIDANS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2021-07-29 | — | — | US | disclosed |
| CN-109134716-B | Vanadium catalyst and method for preparing olefin polymer | 北京引发科技有限公司 | 2020-11-10 | — | — | CN | disclosed |
| US-20190161461-A1 | RIBONUCLEOTIDE REDUCTASE INHIBITORS AND METHODS OF USE | CITY OF HOPE | 2019-05-30 | — | — | US | disclosed |
| US-20180155303-A1 | RIBONUCLEOTIDE REDUCTASE INHIBITORS AND METHODS OF USE | CITY OF HOPE | 2018-06-07 | — | — | US | disclosed |
| US-9796692-B2 | Ribonucleotide reductase inhibitors and methods of use | CITY OF HOPE (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170137392-A1 | RIBONUCLEOTIDE REDUCTASE INHIBITORS AND METHODS OF USE | CITY OF HOPE | 2017-05-18 | — | — | US | disclosed |
| WO-2008015714-A2 | PROCESS FOR THE PREPARATION OF 1,1-DICHLORO-2-ALKYLETHYLENE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008015714-A2 | PROCESS FOR THE PREPARATION OF 1,1-DICHLORO-2-ALKYLETHYLENE | F.I.S. FABBRICA ITALIANA SINTETICI S.P.A. (IT) | 2008-02-07 | — | — | WO | disclosed |
| US-7223769-B2 | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-29 | — | — | US | disclosed |
| EP-1483249-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2006-09-06 | — | — | EP | disclosed |
| US-20050171130-A1 | Pyrimidine compounds and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-0163433-B1 | ANTIBACTERIAL SOLID COMPOSITION FOR ORAL ADMINISTATION | Takeda Chemical Industries, Ltd. (JP) | 1990-08-01 | — | — | EP | disclosed |
| US-4616008-A | LIPID-SOLUBLE CEPHALOSPORINS AND CYCLODEXTRINS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0163433-A2 | Antibacterial solid composition for oral administation | Takeda Chemical Industries, Ltd. (JP) | 1985-12-04 | — | — | EP | disclosed |
| EP-0035357-A1 | 2-Methylcephalosporins and production thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-4112086-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1978-09-05 | — | — | US | disclosed |