Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5087830

C=Cc1ccc(C=C)c(O)c1.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.47
ALDH1A1 P00352 3/20 0.43
LCK P06239 3/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
KDM4E B2RXH2 2/20 0.37
RAB9A P51151 2/20 0.37
PTGS2 P35354 1/20 0.37
TDP1 Q9NUW8 3/20 0.35
POLB P06746 2/20 0.35
BLM P54132 2/20 0.35
GFER P55789 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TP53 P04637 2/20 0.35
ALPL P05186 1/20 0.35
ALPI P09923 1/20 0.35
ALPG P10696 1/20 0.35
TTR P02766 2/20 0.35
MMP2 P08253 2/20 0.35
ALOX5 P09917 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828623 0.98 TRPA1 (0.48) TRPA1ALDH1A1LCKESR1ESR2
SCHEMBL13993600 0.83 KDM4E (0.59) TRPA1ALDH1A1LCKKDM4ERAB9A
SCHEMBL23209631 0.83 TYR (0.48) TRPA1ALDH1A1KDM4ERAB9APTGS2
SCHEMBL1720733 0.79 TRPA1 (0.42) TRPA1ALDH1A1LCKESR2KDM4E
SCHEMBL1720735 0.79 TRPA1 (0.42) TRPA1ALDH1A1LCKESR2KDM4E
SCHEMBL6937034 0.79 TRPA1 (0.42) TRPA1ALDH1A1LCKESR2KDM4E
SCHEMBL465532 0.79 TRPA1 (0.53) TRPA1ALDH1A1LCKESR1ESR2
SCHEMBL29403669 0.78 LCK (0.64) TRPA1ALDH1A1LCKKDM4ERAB9A
SCHEMBL29502822 0.78 TRPA1 (0.52) TRPA1ALDH1A1LCKESR1ESR2
SCHEMBL170797 0.78 LCK (0.64) TRPA1ALDH1A1LCKKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008122929-A1 MATERIAL FOR ACQUISITION OF LIQUIDS AND DISPOSABLE ABSORBENT ARTICLE COMPRISING THE MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2008-10-16 WO disclosed