Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7721938 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Bromide SCHEMBL5091531 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Fluoride Ion SCHEMBL5246642 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL2685431 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Bromide SCHEMBL5088593 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Iodide SCHEMBL5086624 | 0.95 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Phosphine SCHEMBL28106805 | 0.93 | TP53 (0.46) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Fluoride Ion SCHEMBL65871 | 0.93 | TP53 (0.46) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Hydrochloric Acid SCHEMBL2526828 | 0.90 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 | |
| Fluoride Ion SCHEMBL11373889 | 0.90 | TP53 (0.48) | TP53TRPA1TAAR1SIGMAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005896-A | Method for directly synthesizing polyethylene glycol terephthalate from ethylene oxide | 常州大学 | 2024-05-10 | — | — | CN | claimed |
| CN-115637020-A | Hyperbranched epoxy resin thermosetting resin composition and application thereof | 复旦大学 | 2023-01-24 | — | — | CN | claimed |
| US-20250326886-A1 | POLYMER COMPOSITION, EPOXY RESIN COMPOSITION, CURING AGENT FOR EPOXY RESIN, AND FAST CURING ADHESIVE | TORAY FINE CHEMICALS CO., LTD. (JP) | 2025-10-23 | — | — | US | disclosed |
| CN-118005896-A | Method for directly synthesizing polyethylene glycol terephthalate from ethylene oxide | 常州大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117355557-A | Polymer composition, epoxy resin composition, curing agent for epoxy resin, and quick-setting adhesive | 东丽精细化工株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-112010890-B | Synthesis method of 3-mercaptopropyl trialkoxysilane | 江西晨光新材料股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115637020-A | Hyperbranched epoxy resin thermosetting resin composition and application thereof | 复旦大学 | 2023-01-24 | — | — | CN | disclosed |
| WO-2022249966-A1 | POLYMER COMPOSITION, EPOXY RESIN COMPOSITION, CURING AGENT FOR EPOXY RESIN, AND FAST-CURING ADHESIVE | 東レ・ファインケミカル株式会社 | 2022-12-01 | — | — | WO | disclosed |
| CN-107540670-B | Preparation method of 1- (3-chloropyrazolo [1,5a ] -4,5,6, 7-tetrahydropyridine-2-yl) -5-methylamine pyrazole-4-carbonitrile | 湖北相和精密化学有限公司 | 2021-08-13 | — | — | CN | disclosed |
| CN-112010890-A | Synthesis method of 3-mercaptopropyl trialkoxysilane | 江西晨光新材料股份有限公司 | 2020-12-01 | — | — | CN | disclosed |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | disclosed |
| EP-0502707-B1 | Method for production of 3-cyano-3,5,5-trimethyl cyclohexanone | NIPPOH CHEMICALS (JP) | 1995-10-25 | — | — | EP | disclosed |
| US-5179221-A | METHOD FOR PRODUCTION OF 3-CYANO-3,5,5-TRIMETHYL CYCLOHEXANONE | NIPPON CHEMICALS CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0502707-A1 | Method for production of 3-cyano-3,5,5-trimethyl cyclohexanone | NIPPOH CHEMICALS CO., LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| EP-0105762-B1 | PROCESS FOR PRODUCING ANTHRAQUINONE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4519947-A | SULFONATING 1,4-DIAMINO-2,3-DIHALOGENO-ANTHRAQUINONE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-05-28 | — | — | US | disclosed |
| EP-0105762-A2 | Process for producing anthraquinone compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-18 | — | — | EP | disclosed |
| US-4335051-A | AQUEOUS ALKALI HYDROXIDE AS ACID ACCEPTOR WHEN REACTING METHANOL W | BAYER AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| US-4122288-A | Hydrolysis of alkyl substituted dihalobenzene compounds | UOP INC. (US) | 1978-10-24 | — | — | US | disclosed |
| US-3992370-A | 1,1-Dichloro-1a,1b-dihydrodibenzo(b,f)cycloprop(d)azepine-6(1H)-carboxaldehyde | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | TP53 3199/4885TRPA1 4189/4885TAAR1 4519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.