Fluoride Ion

Fluoride Ion

SCHEMBL5246642

CC[P+](CC)(CC)Cc1ccccc1.[F-]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.48
TRPA1 O75762 2/20 0.47
TAAR1 Q96RJ0 4/20 0.44
SIGMAR1 Q99720 4/20 0.44
SLC6A2 P23975 2/20 0.44
MAOA P21397 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
CYP2A6 P11509 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA1 P30542 1/20 0.44
EPHX1 P07099 1/20 0.42
CYP2D6 P10635 2/20 0.41
SLC18A2 Q05940 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride Ion SCHEMBL65871 0.98 TP53 (0.46) TP53TRPA1TAAR1SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL2685431 0.95 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Iodide SCHEMBL5086624 0.95 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Fluoride Ion SCHEMBL11373889 0.95 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Bromide SCHEMBL5088078 0.95 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Water SCHEMBL7721938 0.95 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL2526828 0.90 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Iodide SCHEMBL5086904 0.90 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Hydrochloric Acid SCHEMBL5085369 0.90 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2
Bromide SCHEMBL5091531 0.90 TP53 (0.48) TP53TRPA1TAAR1SIGMAR1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788784-A Preparation method of 2-fluoro-3-trifluoromethylpyridine 山东省农药科学研究院 2021-12-14 CN claimed
EP-1318152-B1 Catalysts and process for preparing polyisocyanates containing isocyanurate groups DEGUSSA (DE) 2007-09-19 EP claimed
US-6875243-B2 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2005-04-05 US claimed
US-20030109665-A1 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2003-06-12 US claimed
EP-1318152-A2 Catalysts and process for preparing polyisocyanates containing isocyanurate groups and their use Degussa AG (DE) 2003-06-11 EP claimed
EP-1318152-B1 Catalysts and process for preparing polyisocyanates containing isocyanurate groups DEGUSSA (DE) 2007-09-19 EP disclosed
US-6875243-B2 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2005-04-05 US disclosed
US-20030109665-A1 Catalysts for preparing polyisocyanates containing isocyanurate groups, and their use DEGUSSA AG (DE) 2003-06-12 US disclosed
EP-1318152-A2 Catalysts and process for preparing polyisocyanates containing isocyanurate groups and their use Degussa AG (DE) 2003-06-11 EP disclosed