Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4117987 | 0.81 | PTGIR (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6958282 | 0.80 | PTGIR (0.46) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7722638 | 0.80 | MAPT (0.50) | MEN1KMT2AALDH1A1CYP1A2TDP1 | |
| SCHEMBL7081529 | 0.78 | PTGIR (0.52) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL864716 | 0.73 | MAPT (0.61) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10280961 | 0.72 | SCN9A (0.50) | SLC18A3 | |
| SCHEMBL13942035 | 0.72 | SCN9A (0.50) | SLC18A3 | |
| SCHEMBL5635981 | 0.72 | TDP1 (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5799404 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL14943051 | 0.71 | CA1 (0.50) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018692-A1 | NOVEL CHALCONE DERIVATIVES WHICH INHIBIT THE IL-5 ACTIVITY | THE INDUSTRY AND ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (KR) | 2008-02-14 | — | — | WO | disclosed |