Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 19/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443818 | 0.84 | LTB4R2 (0.59) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL5091114 | 0.81 | LTB4R2 (0.43) | LTB4R2AGTR1 | |
| SCHEMBL5089013 | 0.80 | LTB4R2 (0.48) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL18425480 | 0.77 | LTB4R2 (0.69) | LTB4R2AGTR1 | |
| SCHEMBL443650 | 0.75 | LTB4R2 (0.65) | LTB4R2AGTR1 | |
| SCHEMBL443942 | 0.74 | LTB4R2 (0.62) | LTB4R2AGTR1 | |
| SCHEMBL8260354 | 0.74 | LTB4R2 (0.52) | LTB4R2AGTR1 | |
| SCHEMBL9590866 | 0.73 | AGTR1 (0.71) | LTB4R2AGTR1AGTR2 | |
| SCHEMBL446695 | 0.71 | LTB4R2 (0.58) | LTB4R2AGTR1 | |
| SCHEMBL5099365 | 0.71 | LTB4R2 (0.58) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417052-B2 | Phenylene derivative having tetrazole ring or thiazolidinedione ring | SANKYO COMPANY, LIMITED (JP) | 2008-08-26 | — | — | US | disclosed |
| US-20070105846-A1 | Phenylene derivative having tetrazole ring or thiazolidinedione ring | RENASCIENCE CO., LTD (JP) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105846-A1 | Phenylene derivative having tetrazole ring or thiazolidinedione ring | JAK2, ABL1, CYP3A5 | LTB4R2 1259/4885AGTR1 41/4885AGTR2 31/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.