Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.70 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.70 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.70 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.70 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.70 |
| ▸ | FPR3 | P25089 | 1/20 | 0.70 |
| ▸ | HTR1D | P28221 | 1/20 | 0.70 |
| ▸ | HTR1B | P28222 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL522981 | 1.00 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL522982 | 1.00 | ADRB2 (0.70) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL3438774 | 0.93 | ADRB2 (0.60) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL29623614 | 0.86 | ADRB2 (0.79) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL185284 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL28335201 | 0.86 | ADRB2 (0.79) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL185285 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL28335190 | 0.86 | ADRB2 (0.76) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL197442 | 0.86 | ADRB2 (0.79) | ADRB2ADRB1ADRB3ADRA1DKDM4E | |
| SCHEMBL185460 | 0.86 | ADRB2 (0.79) | ADRB2ADRB1ADRB3ADRA1DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026080-B | Pyrazolyl-substituted heteroaryl compounds and their use as medicaments | 勃林格殷格翰国际有限公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-1885684-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE BETA-2 ADRENERGIC RECEPTOR | Laboratorios Almirall, S.A. (ES) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006122788-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-11-23 | — | — | WO | disclosed |