Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5091339 | 0.99 | F10 (0.47) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL2997836 | 0.86 | F10 (0.55) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL5094210 | 0.85 | F10 (0.54) | F10PRSS1ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL5089043 | 0.85 | F10 (0.54) | F10PRSS1ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL5099667 | 0.85 | F10 (0.53) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL7560895 | 0.83 | F10 (0.46) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL7563218 | 0.83 | F10 (0.46) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL5098937 | 0.82 | NPC1 (0.42) | F10PRSS1ALDH1A1LMNAHPGD | |
| Hydrochloric Acid SCHEMBL7560857 | 0.82 | F10 (0.45) | F10PRSS1ALDH1A1LMNAHPGD | |
| SCHEMBL7114691 | 0.80 | F10 (0.54) | F10PRSS1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7425641-B2 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2008-09-16 | — | — | US | claimed |
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065346-A1 | Carboxylic acid amides, the preparation thereof and their use as pharmaceutical compositions | F12, F11, F2 | F10 23/4885PRSS1 957/4885ALDH1A1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.