Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.71 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 2/20 | 0.54 |
| ▸ | AGXT | P21549 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3364162 | 0.89 | MAOB (0.69) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL4334893 | 0.88 | MAOB (0.68) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL13577127 | 0.86 | MAOB (0.66) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL157731 | 0.86 | MAOB (0.66) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL5096562 | 0.85 | MAOB (0.50) | MAOBPARP10IDO1 | |
| SCHEMBL16113499 | 0.84 | MAOB (0.51) | MAOBPARP10IDO1AGXT | |
| SCHEMBL4339811 | 0.84 | MAOB (0.62) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL29638127 | 0.83 | MAOB (1.00) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL1379497 | 0.83 | MAOB (1.00) | MAOBPARP10NR4A2MAOAIDO1 | |
| SCHEMBL1336477 | 0.83 | MAOB (0.61) | MAOBPARP10NR4A2MAOAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722929-B2 | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators | VALEANT PHARMACEUTICALS INTERNATIONAL (US) | 2014-05-13 | — | — | US | disclosed |
| US-20080188561-A1 | N-[2-AMINO-4-(PHENYLMETHOXY)PHENYL] AMIDES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS | JPMORGAN CHASE BANK, N.A. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188561-A1 | N-[2-AMINO-4-(PHENYLMETHOXY)PHENYL] AMIDES AND RELATED COMPOUNDS AS POTASSIUM CHANNEL MODULATORS | KCNB2, KCNJ2, KCNA2 | MAOB 808/4885PARP10 2373/4885NR4A2 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.