Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.41 |
| ▸ | HTR1A | P08908 | 8/20 | 0.41 |
| ▸ | HTR2B | P41595 | 8/20 | 0.41 |
| ▸ | HTR5A | P47898 | 7/20 | 0.41 |
| ▸ | HTR1D | P28221 | 6/20 | 0.41 |
| ▸ | HTR1B | P28222 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | HTR1E | P28566 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5089892 | 0.74 | AR (0.45) | HTR7HTR1AHTR2BHTR5AHTR1D | |
| SCHEMBL11460691 | 0.72 | APP (0.44) | HTR7HTR1AHTR2BHTR5AHTR1D | |
| SCHEMBL8802694 | 0.70 | KDM4E (0.48) | HTR7ARPGRKDM4EALDH1A1 | |
| SCHEMBL30870726 | 0.69 | AR (0.49) | HTR7ARPGRSTK10CLK2 | |
| SCHEMBL1436484 | 0.68 | FYN (0.56) | HTR7ARPGRSQOR | |
| SCHEMBL8107730 | 0.68 | APP (0.41) | HTR7ARPGRKDM4EALDH1A1 | |
| SCHEMBL9469524 | 0.68 | HTR7 (0.55) | HTR7ARPGRSTK10CLK2 | |
| SCHEMBL301996 | 0.68 | CA1 (0.71) | HTR7KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL1133173 | 0.68 | KCNN4 (0.54) | HTR7ARPGRKDM4EALDH1A1 | |
| SCHEMBL29788337 | 0.68 | CA1 (0.71) | HTR7KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091594-A2 | FUNGICIDAL MIXTURES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-31 | — | — | WO | disclosed |