SCHEMBL5090368

SCHEMBL5090368

O=C1c2c(Br)c(Br)c(Br)c(Br)c2C(=O)N1CCCCN1C(=O)c2c(Br)c(Br)c(Br)c(Br)c2C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA4 P22748 1/20 0.46
FAAH O00519 2/20 0.39
MGLL Q99685 2/20 0.39
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 2/20 0.37
RECQL P46063 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSP90AA1 P07900 1/20 0.37
TLR9 Q9NR96 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570337 0.98 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL10570526 0.98 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL11295187 0.95 CA1 (0.46) CA12CA1CA2CA7CA9
SCHEMBL29366486 0.90 CA9 (0.49) CA12CA1CA2CA7CA9
SCHEMBL94242 0.90 CA9 (0.49) CA12CA1CA2CA7CA9
SCHEMBL7932533 0.88 PTGS1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL3683409 0.87 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL10933086 0.81 CA9 (0.44) CA12CA1CA2CA7CA9
SCHEMBL8912698 0.81 CA9 (0.44) CA12CA1CA2CA7CA9
SCHEMBL6046957 0.79 CA9 (0.43) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4535170-A BIS-BROMOPHTHALIMIDES RAYCHEM CORPORATION (US) 1985-08-13 US claimed
US-4374220-A FIREPROOFING; INFLAMMABLE POLYMERIC MACROMOLECULES; HEAT RESISTANCE RAYCHEM CORPORATION (US) 1983-02-15 US claimed
JP-60173029-A None JP disclosed
US-20080303006-A1 FLAME RETARDANT THERMOPLASTIC RESINOUS COMPOSTION CITIBANK, N.A., AS COLLATERAL AGENT 2008-12-11 US disclosed
US-20060292450-A1 Non-aqueous electrolyte secondary battery MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2006-12-28 US disclosed
EP-1405879-A1 FLAME RETARDANT POLYETHYLENE TEREPHTHALATE RESIN COMPOSITION Win Tech Polymer Ltd. (JP) 2004-04-07 EP disclosed
US-5668201-A Flame retardant graft copolymer composition GENERAL ELECTRIC COMPANY (US) 1997-09-16 US disclosed
US-4873341-A White bis-imide flame retardants ETHYL CORPORATION (US) 1989-10-10 US disclosed
EP-0219014-A2 Flame retardant elastomeric compositions GENERAL ELECTRIC COMPANY (US) 1987-04-22 EP disclosed
US-4639486-A POLYETHERIMIDE ESTER AND HALOGENATED MATERIAL GENERAL ELECTRIC COMPANY (US) 1987-01-27 US disclosed
US-4552911-A TETRAHALOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1985-11-12 US disclosed
JP-S60173029-A FLAME-RETARDING COMPOSITION HITACHI CABLE LTD 1985-09-06 JP disclosed
EP-0042561-B1 FIRE-PROOFED MOULDING MASSES BASED ON AROMATIC THERMOPLASTIC POLYESTERS, PROCESS FOR ITS PREPARATION AND USE IN THE PRODUCTION OF SHAPED ARTICLES BAYER AG (DE) 1985-03-27 EP disclosed
EP-0086353-A1 Polycarbonate moulding compounds with flame resistance BAYER AG (DE) 1983-08-24 EP disclosed
US-4366276-A Flame-resistant moulding materials based on thermoplastic aromatic polyesters and polyesters carbonates, a process for their production and their use in the production of moulded bodies BAYER AKTIENGESELLSCHAFT (DE) 1982-12-28 US disclosed
EP-0042561-A1 Fire-proofed moulding masses based on aromatic thermoplastic polyesters, process for its preparation and use in the production of shaped articles BAYER AG (DE) 1981-12-30 EP disclosed
US-4208489-A AN ALKALI METAL SALT AND A TETRAHALOGENOPHTHALIMIDE BAYER AKTIENGESELLSCHAFT (DE) 1980-06-17 US disclosed