SCHEMBL8912698

SCHEMBL8912698

O=C1c2c(Br)c(Br)c(Br)c(Br)c2C(=O)N1CCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 5/20 0.44
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA7 P43166 4/20 0.44
CA12 O43570 3/20 0.44
CA4 P22748 2/20 0.44
KDM4E B2RXH2 3/20 0.41
HEXA P06865 1/20 0.40
HEXB P07686 1/20 0.40
KMT2A Q03164 3/20 0.34
ALDH1A1 P00352 2/20 0.34
PABPC1 P11940 2/20 0.34
MEN1 O00255 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
RGS12 O14924 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366486 0.85 CA9 (0.49) CA9CA1CA2CA7CA12
SCHEMBL94242 0.85 CA9 (0.49) CA9CA1CA2CA7CA12
SCHEMBL7562782 0.81 CA9 (0.41) CA9CA1CA2CA7CA12
SCHEMBL5090368 0.81 CA12 (0.46) CA9CA1CA2CA7CA12
SCHEMBL11295187 0.81 CA1 (0.46) CA9CA1CA2CA7CA12
SCHEMBL6570337 0.79 CA12 (0.45) CA9CA1CA2CA7CA12
SCHEMBL10570526 0.79 CA12 (0.45) CA9CA1CA2CA7CA12
SCHEMBL28720746 0.78 KDM4E (0.45) KDM4EHEXAHEXBKMT2AALDH1A1
SCHEMBL11000698 0.78 KDM4E (0.47) CA9CA1CA2CA7CA12
SCHEMBL10933086 0.77 CA9 (0.44) CA9CA1CA2CA7CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3966663-A TETRABROMO COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-06-29 US claimed
US-5693797-A REACTING TETRABROMOPHTHALIC ANHYDRIDE, AN ORGANIC ACID, AN ACID DISPERSING AGENT AND AN AMINE IN WATER DECREASES PROCESS TIME, YELLOWING AND PARTICLE SIZES BUT INCREASES WHITENESS AND PURITY UNITEX CHEMICAL CORPORATION (US) 1997-12-02 US disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed
US-4585806-A HALOGENATED IMIDE-CONTAINING OPOLYOL ETHYL CORPORATION (US) 1986-04-29 US disclosed
US-4564468-A HALOGENATED IMIDE POLYOL ETHYL CORPORATION (US) 1986-01-14 US disclosed
US-4515964-A Polyhalophthalimidoalkyl-functional carbonates PPG INDUSTRIES, INC. (US) 1985-05-07 US disclosed
US-4414396-A FIREPROOFING PPG INDUSTRIES, INC. (US) 1983-11-08 US disclosed
US-4401778-A HALOGENATED IMIDE-CONTAINING POLYOLS SAYTECH, INC. (US) 1983-08-30 US disclosed
US-4003862-A N-substituted tetrahalophthalimides as flame retardants MICHIGAN CHEMICAL CORPORATION (US) 1977-01-18 US disclosed
US-3966663-A TETRABROMO COMPOUND THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-06-29 US disclosed