Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.89 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | IDE | P14735 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | FGF1 | P05230 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL565396 | 0.95 | TDP1 (0.98) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL9168421 | 0.95 | TDP1 (0.98) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL9171752 | 0.94 | TDP1 (0.96) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL305706 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL31429755 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL13510665 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL12424058 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL10171640 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL305707 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 | |
| SCHEMBL564538 | 0.94 | TDP1 (1.00) | TDP1FOLH1CAPN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232049-B2 | Ligating preferential oligonucleotide and labeled detection nucleotide sequences to bridge oligonucleotide; designing DNA reporter molecules | CASE WESTERN RESERVE UNIVERSITY (US) | 2012-07-31 | — | — | US | disclosed |
| US-20080176233-A1 | METHOD FOR DETECTING SMALL OLIGONUCLEOTIDES | CASE WESTERN RESERVE UNIVERSITY | 2008-07-24 | — | — | US | disclosed |
| WO-2006014625-A1 | METHODS AND COMPOSITIONS FOR DETECTION OF SMALL INTERFERING RNA AND MICRO-RNA | ILLUMINA, INC. ET AL. (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060019258-A1 | Methods and compositions for detection of small interfering RNA and micro-RNA | ILLUMINA, INC. (US) | 2006-01-26 | — | — | US | disclosed |
| US-6133038-A | Platinum-containing compounds methods for their preparation and applications thereof | KREATECH DIAGNOSTICS (NL) | 2000-10-17 | — | — | US | disclosed |
| US-5985566-A | Platinum-containing compounds, methods for their preparation and applications thereof | KREATECH DIAGNOSTICS (NL) | 1999-11-16 | — | — | US | disclosed |
| US-5714327-A | PLATINUM CONTAINING DETECTABLE PROBE COMPOUND HAVING MARKER MOIETY, STABILIZING SUBSTITUENTS, BIOMOLECULE | KREATECH DIAGNOSTICS (NL) | 1998-02-03 | — | — | US | disclosed |
| EP-0379949-A2 | Method for the determination of HIV antibodies | Roche Diagnostics GmbH (DE) | 1990-08-01 | — | — | EP | disclosed |