Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.70 |
| ▸ | RARB | P10826 | 5/20 | 0.67 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10616405 | 0.99 | TP53 (0.75) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10616413 | 0.99 | TP53 (0.75) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9868849 | 0.95 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9869039 | 0.93 | TP53 (0.75) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10415543 | 0.93 | MAPK1 (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10417399 | 0.91 | TP53 (0.68) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10525662 | 0.90 | TP53 (0.70) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8080211 | 0.89 | MAPK1 (0.73) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8081866 | 0.88 | PLA2G4B (0.64) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL8436025 | 0.88 | MAPK1 (0.67) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435333-B2 | Photo-switchable membrane and method | UNIVERSITY OF ROCHESTER (US) | 2013-05-07 | — | — | US | disclosed |
| US-20120025136-A1 | PHOTO-SWITCHABLE MEMBRANE AND METHOD | UNIVERSITY OF ROCHESTER (US) | 2012-02-02 | — | — | US | disclosed |