Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.73 |
| ▸ | RARB | P10826 | 5/20 | 0.69 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10525662 | 0.94 | TP53 (0.70) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10616413 | 0.94 | TP53 (0.75) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10616405 | 0.94 | TP53 (0.75) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9868849 | 0.94 | TP53 (0.69) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10417399 | 0.93 | TP53 (0.68) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL509130 | 0.93 | TP53 (0.72) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9515560 | 0.90 | TP53 (0.68) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL9711933 | 0.90 | TP53 (0.68) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL10415543 | 0.88 | MAPK1 (0.65) | TP53TSHRPLA2G4BRARBPLA2G4A | |
| SCHEMBL1163918 | 0.86 | TP53 (1.00) | TP53TSHRPLA2G4BRARBPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981967-A | Pyrimidine compounds and their use as liquid crystals | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1991-01-01 | — | — | US | disclosed |