Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713876 | 0.78 | POLB (0.59) | KDM1AKMT2AGAAMEN1LMNA | |
| SCHEMBL4747178 | 0.78 | KDM1A (0.54) | KDM1AGAALMNAHTTMAPT | |
| SCHEMBL17993533 | 0.78 | KDM1A (0.70) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL5093996 | 0.77 | GAA (0.53) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL13416408 | 0.77 | KDM1A (0.68) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL968912 | 0.75 | CA1 (0.64) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL29807803 | 0.74 | GAA (0.61) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL3859948 | 0.74 | GAA (0.61) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL3223491 | 0.74 | KDM1A (0.60) | KDM1AKMT2AGAAMEN1NPC1 | |
| SCHEMBL10955276 | 0.73 | KDM1A (0.59) | KDM1AKMT2AGAAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008508348-A | — | — | 2008-03-21 | — | — | JP | claimed |
| EP-1796681-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | Genmedica Therapeutics SL (ES) | 2007-06-20 | — | — | EP | claimed |
| WO-2006013209-A2 | COMPOUNDS FOR INHIBITING COPPER-CONTAINING AMINE OXIDASES AND USES THEREOF | GENMEDICA THERAPEUTICS SL (ES) | 2006-02-09 | — | — | WO | claimed |