Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5100944 | 0.89 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5094179 | 0.88 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL1376506 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6585919 | 0.83 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL6580323 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL6973897 | 0.83 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL5094145 | 0.83 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5107053 | 0.81 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5097621 | 0.78 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5100507 | 0.77 | PTGS2 (0.71) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263751-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-06-16 | — | — | EP | claimed |
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2003-12-18 | — | — | US | claimed |
| US-7354936-B2 | 2-phenylpyran-4-one derivatives | ALMIRALL AG (CH) | 2008-04-08 | — | — | US | disclosed |
| EP-1263751-B1 | 2-PHENYLPYRAN-4-ONE DERIVATIVES | ALMIRALL PRODESFARMA AG (CH) | 2004-06-16 | — | — | EP | disclosed |
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232880-A1 | 2-Phenylpyran-4-one derivatives | CYP3A4, UGT1A4, CYP4B1 | PTGS2 103/4885PTGS1 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.