Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5094330 | 1.00 | MEN1 (0.54) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL7275053 | 0.86 | MEN1 (0.42) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL22034863 | 0.85 | MEN1 (0.63) | MEN1GAAKMT2AGRIK1GRIK2 | |
| SCHEMBL1274536 | 0.85 | MEN1 (0.66) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL28763685 | 0.84 | SMN1; SMN2 (0.44) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL6131636 | 0.82 | MEN1 (0.42) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL590719 | 0.81 | MEN1 (0.41) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL25955311 | 0.81 | MEN1 (0.41) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL25407355 | 0.80 | MEN1 (0.60) | MEN1GAAKMT2AAAK1TDP1 | |
| SCHEMBL28560564 | 0.80 | MEN1 (0.60) | MEN1GAAKMT2AAAK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699173-A1 | GEM-DISUBSTITUTED PYRROLIDINES, PIPERAZINES, AND DIAZEPANES, AND COMPOSITIONS AND METHODS OF MAKING THE SAME | California Institute of Technology (US) | 2020-08-26 | — | — | EP | disclosed |
| US-20080032985-A1 | 4-Substituted Quinoline Derivatives, Method and Intermediates for Their Preparation and Pharmaceutical Compositions Containing Them | NOVEXEL (FR) | 2008-02-07 | — | — | US | disclosed |
| EP-1763527-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES, METHOD AND INTERMEDIATES FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | NOVEXEL (FR) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006010831-A1 | 4-SUBSTITUTED QUINOLINE DERIVATIVES, METHOD AND INTERMEDIATES FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | NOVEXEL (FR) | 2006-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032985-A1 | 4-Substituted Quinoline Derivatives, Method and Intermediates for Their Preparation and Pharmaceutical Compositions Containing Them | CYP3A7, CYP3A4, CYP4B1 | MEN1 1529/4885GAA 778/4885KMT2A 3191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.