Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28215001 | 0.98 | KDM4E (0.56) | KDM4EMAPTPOLBTSHRHPGD | |
| Hydrochloric Acid SCHEMBL2529687 | 0.98 | KDM4E (0.56) | KDM4EMAPTPOLBTSHRHPGD | |
| Dioxane SCHEMBL28219405 | 0.88 | KDM4E (0.49) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL510475 | 0.86 | MAPT (0.50) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL22066831 | 0.86 | KDM4E (0.50) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL510473 | 0.86 | KDM4E (0.50) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL508942 | 0.86 | KDM4E (0.50) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL9780872 | 0.84 | CYP3A4 (0.47) | KDM4EMAPTPOLBGAAMEN1 | |
| SCHEMBL12214120 | 0.83 | KDM4E (0.42) | KDM4EMAPTPOLBTSHRHPGD | |
| SCHEMBL510321 | 0.82 | KDM4E (0.47) | KDM4EMAPTPOLBTSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850059-B | Improved synthesis process of 2,4, 6-trimethylphenylacetyl chloride | 大连奇凯医药科技有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-115850059-A | Improved synthesis process of 2,4, 6-trimethylbenzene acetyl chloride | 大连奇凯医药科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114394895-A | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2022-04-26 | — | — | CN | claimed |
| US-9783654-B2 | Additives and methods for terminating polymerization and/or reducing viscosity of polymer solution | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2017-10-10 | — | — | US | claimed |
| US-20130158174-A1 | ADDITIVES AND METHODS FOR TERMINATING POLYMERIZATION AND/OR REDUCING VISCOSITY OF POLYMER SOLUTION | BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) | 2013-06-20 | — | — | US | claimed |
| EP-0665212-B1 | Process for the preparation of 2,4,6-trimethylphenylacetic acid | BAYER AG (DE) | 1999-06-09 | — | — | EP | claimed |
| US-20260068886-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2026-03-12 | — | — | US | disclosed |
| WO-2024050016-A9 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-04-03 | — | — | WO | disclosed |
| CN-115850059-B | Improved synthesis process of 2,4, 6-trimethylphenylacetyl chloride | 大连奇凯医药科技有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-114394895-B | Preparation method of 2,4, 6-trimethylphenylacetic acid | 西安凯立新材料股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0698010-A1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5491172-A | ACYLCOENZYME A:CHOLESTEROL ACYLTRANSFERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0676388-A2 | Process for the preparation of phenylacetic acid derivatives and intermediate products | BAYER AG (DE) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994026702-A1 | N-ACYL SULFAMIC ACID ESTERS (OR THIOESTERS), N-ACYL SULFONAMIDES, AND N-SULFONYL CARBAMIC ACID ESTERS (OR THIOESTERS) AS HYPERCHOLESTEROLEMIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |
| EP-0528156-A1 | 3-Aryl-4-hydroxy-delta3-dihydrofuranone and 3-aryl-4-hydroxy-delta3-dihydrothiophenone derivatives | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| US-4544450-A | Electrochemical process for the synthesis of organic compounds | ANIC S.P.A. (IT) | 1985-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260068886-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | CRBN, STUB1, CUL1 | KDM4E 928/4885MAPT 3939/4885POLB 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.