Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2357618 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL11556182 | 0.85 | — | — | |
| SCHEMBL22416505 | 0.84 | — | — | |
| SCHEMBL3182945 | 0.79 | SNCA (0.41) | CA12CA2CA9CA1SNCA | |
| SCHEMBL906315 | 0.77 | — | — | |
| SCHEMBL6284240 | 0.77 | — | — | |
| SCHEMBL19630043 | 0.76 | CA12 (0.37) | CA12CA2CA9CA1SNCA | |
| SCHEMBL8694711 | 0.75 | GNAI3 (0.50) | CA12CA2CA9CA1SNCA | |
| SCHEMBL1477624 | 0.74 | — | — | |
| SCHEMBL476457 | 0.74 | GNAI3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116425938-A | Flame-retardant polyurethane soft foam with excellent mechanical properties and preparation method thereof | 江苏米尔化工科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116285775-A | High-performance chloroprene rubber adhesive and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116102700-A | Softening agent and preparation method thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116041665-A | Preparation method of isocyanate curing agent with high trimer content | 南京工业大学 | 2023-05-02 | — | — | CN | claimed |
| CN-116023614-A | High-fluidity flame-retardant polyurethane soft foam composition | 江苏米尔化工科技有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-112961303-B | Softening agent for soft polyurethane foam and application thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-112961303-A | Softening agent for soft polyurethane foam and application thereof | 江苏奥斯佳材料科技股份有限公司 | 2021-06-15 | — | — | CN | claimed |
| CN-112940212-A | Polyurethane catalyst, automotive polyurethane material and preparation method thereof | 江苏奥斯佳材料科技股份有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-116425938-A | Flame-retardant polyurethane soft foam with excellent mechanical properties and preparation method thereof | 江苏米尔化工科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-116285775-A | High-performance chloroprene rubber adhesive and preparation method thereof | 上谷新材料(苏州)有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116041665-A | Preparation method of isocyanate curing agent with high trimer content | 南京工业大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-116023614-A | High-fluidity flame-retardant polyurethane soft foam composition | 江苏米尔化工科技有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-112251820-B | VEGFR-2 inhibitor screening method, VEGFR-2 inhibitor and antitumor drug | 绍兴文理学院 | 2023-02-17 | — | — | CN | disclosed |
| CN-112961303-B | Softening agent for soft polyurethane foam and application thereof | 江苏奥斯佳材料科技股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| US-20090264422-A1 | METHOD OF TREATING DISEASE STATES USING SUBSTITUTED PYRAZOLE COMPOUNDS | MIIKANA THERAPEUTICS, INC. | 2009-10-22 | — | — | US | disclosed |
| US-7563787-B2 | Substituted pyrazole compounds | MIIKANA THERAPEUTICS, INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20070142368-A1 | Substituted pyrazole compounds | MIIKANA THERAPEUTICS, INC. | 2007-06-21 | — | — | US | disclosed |
| US-4353826-A | ANTITUBERCULAR ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1982-10-12 | — | — | US | disclosed |
| US-4261891-A | BACTERICIDES, ANTITUBERCULAR AGENTS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142368-A1 | Substituted pyrazole compounds | AURKC, AURKA, AURKB | CA12 3967/4885CA2 2719/4885CA9 3471/4885 |
| US-20090264422-A1 | METHOD OF TREATING DISEASE STATES USING SUBSTITUTED PYRAZOLE COMPOUNDS | AURKC, AURKA, AURKB | CA12 2932/4885CA2 1677/4885CA9 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.