Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188751 | 0.83 | GAA (0.42) | AGERHTTMAPTMCOLN3GAA | |
| Methyl Alcohol SCHEMBL28016005 | 0.73 | GAA (0.56) | HTTMAPTMCOLN3GAACA1 | |
| Methyl Alcohol SCHEMBL21523587 | 0.73 | GAA (0.56) | HTTMAPTMCOLN3GAACA1 | |
| Methyl Alcohol SCHEMBL3617702 | 0.73 | GAA (0.56) | HTTMAPTMCOLN3GAACA1 | |
| SCHEMBL6917586 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 | |
| SCHEMBL20583857 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 | |
| SCHEMBL10663598 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 | |
| SCHEMBL22615914 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 | |
| SCHEMBL11815250 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 | |
| SCHEMBL8943267 | 0.73 | GAA (0.62) | MAPTMCOLN3GAACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439395-B2 | Process for the preparation of guanidinium salts | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | claimed |
| US-7439395-B2 | Process for the preparation of guanidinium salts | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20070135645-A1 | Process for the preparation of guanidinium salts | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135645-A1 | Process for the preparation of guanidinium salts | GMPS, AGPS, PFAS | AGER 1862/4885HTT 1853/4885MAPT 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.