SCHEMBL5097015

SCHEMBL5097015

CC1CCN(Cc2c(-c3c(F)cc(F)cc3F)c(Cl)nc3ncnn23)CC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 19/20 0.39
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5090639 0.88 PDE2A (0.42) PDE2AALDH1A1
SCHEMBL5096873 0.87 PDE2A (0.39) PDE2AALDH1A1
SCHEMBL5103097 0.86 PDE2A (0.38) PDE2AALDH1A1
SCHEMBL81282 0.83 TSHR (0.41) PDE2AALDH1A1
SCHEMBL5094364 0.82 PDE2A (0.35) PDE2A
SCHEMBL5096959 0.80 PDE2A (0.34) PDE2AALDH1A1
SCHEMBL974313 0.78 PDE2A (0.38) PDE2AALDH1A1
SCHEMBL20439999 0.78 EGLN2 (0.42) PDE2AALDH1A1
SCHEMBL977655 0.78 PDE2A (0.35) PDE2AALDH1A1
SCHEMBL5096856 0.77 ALDH1A1 (0.38) PDE2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080076785-A1 7-Aminomethyl-1,2,4-Triazolo[1,5-A]Pyrimidine Compounds And Their Use For Controlling Pathogenic Fungi BASF AKTIENGESELLSCHAFT (DE) 2008-03-27 US disclosed
EP-1797097-A1 7-AMINOMETHYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2007-06-20 EP disclosed
WO-2006034848-A1 7-AMINOMETHYL-1,2,4-TRIAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-04-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076785-A1 7-Aminomethyl-1,2,4-Triazolo[1,5-A]Pyrimidine Compounds And Their Use For Controlling Pathogenic Fungi H1-0, NAT1, DPM1 PDE2A 3313/4885ALDH1A1 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.