Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30051597 | 0.88 | LTA4H (0.61) | CTSCOPRD1OPRM1OPRK1ALPI | |
| SCHEMBL30252512 | 0.88 | LTA4H (0.61) | CTSCOPRD1OPRM1OPRK1ALPI | |
| SCHEMBL10972687 | 0.88 | CTSC (0.57) | CTSCOPRD1OPRM1OPRK1ALPI | |
| SCHEMBL10971927 | 0.88 | CTSC (0.57) | CTSCOPRD1OPRM1OPRK1ALPI | |
| SCHEMBL23194392 | 0.88 | CTSC (0.60) | CTSCOPRD1OPRM1OPRK1ALPI | |
| SCHEMBL8787479 | 0.88 | LTA4H (0.64) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL1711543 | 0.88 | LTA4H (0.64) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL1711542 | 0.88 | LTA4H (0.64) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL11113147 | 0.88 | LTA4H (0.64) | CTSCALPIPKMPTGS1XIAP | |
| SCHEMBL30025974 | 0.88 | LTA4H (0.64) | CTSCALPIPKMPTGS1XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414106-B2 | Synthesis of peptide α-thioesters | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) | 2008-08-19 | — | — | US | disclosed |
| US-20070129537-A1 | Synthesis of peptide alpha-thioesters | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2007-06-07 | — | — | US | disclosed |