Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.69 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14287689 | 0.83 | HRH3 (0.68) | HRH3ACACBKDM4E | |
| SCHEMBL5093660 | 0.83 | HRH3 (0.88) | HRH3 | |
| SCHEMBL5100209 | 0.82 | HRH3 (1.00) | HRH3 | |
| SCHEMBL6369681 | 0.81 | HRH3 (0.61) | HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL5093907 | 0.81 | HRH3 (0.98) | HRH3 | |
| SCHEMBL6070938 | 0.76 | HRH3 (1.00) | HRH3 | |
| SCHEMBL14287571 | 0.76 | HRH3 (1.00) | HRH3 | |
| Hydrochloric Acid SCHEMBL5100243 | 0.76 | HRH3 (0.98) | HRH3 | |
| SCHEMBL14287597 | 0.76 | HRH3 (0.93) | HRH3 | |
| SCHEMBL14287732 | 0.75 | HRH3 (0.71) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |