⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28825581 | 0.97 | — | — | |
| SCHEMBL27944025 | 0.95 | MEN1 (0.42) | — | |
| SCHEMBL29097726 | 0.89 | DPP4 (0.52) | — | |
| SCHEMBL50198 | 0.86 | DPP4 (0.53) | — | |
| SCHEMBL50461 | 0.84 | DPP4 (0.56) | — | |
| SCHEMBL6789363 | 0.82 | MEN1 (0.36) | — | |
| 2,5-Thiophenenedicarboxaldehyde SCHEMBL178830 | 0.80 | — | — | |
| SCHEMBL11066604 | 0.78 | TNFRSF1A (0.39) | — | |
| SCHEMBL4317739 | 0.78 | TNFRSF1A (0.39) | — | |
| SCHEMBL12018834 | 0.78 | RAB9A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2625 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071573-A | Porphyrin framework polymer and preparation method and application thereof | 湘潭大学 | 2026-05-22 | — | — | CN | claimed |
| CN-120081836-A | Response near infrared fluorescent probe targeting butyrylcholinesterase and beta amyloid, and preparation method and application thereof | 湖北大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119954841-A | Preparation method and application of near infrared two-window fluorescent contrast agent | 山东第一医科大学(山东省医学科学院) | 2025-05-09 | — | — | CN | claimed |
| CN-119954789-A | Preparation method of terpyridine fluorescent compound | 河南维诺生物科技有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119751411-A | Aggregation-induced emission probe design, synthesis and sterilization application based on bioorthogonal reaction metabolism anchoring living bacteria strategy | 华南农业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119751429-A | Fluorescent probe with pH value and viscosity response functions and preparation and application thereof | 贵州医科大学 | 2025-04-04 | — | — | CN | claimed |
| CN-118638099-B | Difunctional fluorescent molecular probe, preparation method thereof and application thereof in detection of copper ions and glyphosate in Chinese herbal medicine | 东北农业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119256690-B | Formula and application method of complementary sowing of seeds of degenerated desert grassland | 内蒙古自治区农牧业科学院 | 2025-03-21 | — | — | CN | claimed |
| CN-119256690-A | Formula and application method of complementary sowing of seeds of degenerated desert grassland | 内蒙古自治区农牧业科学院 | 2025-01-07 | — | — | CN | claimed |
| CN-118852142-A | Photosensitizer with hydrogen sulfide release performance and preparation method and application thereof | 四川大学 | 2024-10-29 | — | — | CN | claimed |
| EP-1452522-A2 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-09-01 | — | — | EP | claimed |
| US-20040147745-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2004-07-29 | — | — | US | claimed |
| EP-1178958-B1 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARM INC (US) | 2004-02-18 | — | — | EP | claimed |
| WO-2003076403-A1 | 1,2-DISUBSTITUDED-6-OXO-3-PHENYL-PIPERIDINE-3-CARBOXAMIDES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2003-09-18 | — | — | WO | claimed |
| US-20030171588-A1 | 1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2003-09-11 | — | — | US | claimed |
| US-20030096796-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2003-05-22 | — | — | US | claimed |
| JP-2002539191-A | — | — | 2002-11-19 | — | — | JP | claimed |
| US-6455502-B1 | Compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-09-24 | — | — | US | claimed |
| EP-1178958-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-02-13 | — | — | EP | claimed |
| WO-2000055125-A2 | N-CYANOMETHYL AMIDES AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |