Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.45 |
| ▸ | CCR5 | P51681 | 3/20 | 0.45 |
| ▸ | CCR8 | P51685 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23037082 | 0.99 | CCR1 (0.46) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL5095149 | 0.87 | CCR1 (0.37) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL26287430 | 0.79 | CYP1A2 (0.51) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL31722547 | 0.77 | CCNT1 (0.39) | CCR1CCR5CCR8KDM4ETDP1 | |
| SCHEMBL9327184 | 0.75 | S1PR1 (0.40) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL4581614 | 0.75 | CCR1 (0.56) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL14401330 | 0.74 | CCNT1 (0.42) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL2536206 | 0.73 | CCR1 (0.55) | CCR1CCR5CCR8LMNAKDM4E | |
| SCHEMBL11492995 | 0.72 | CA1 (0.44) | LMNAKDM4ESMN1; SMN2POLBNPSR1 | |
| SCHEMBL31482561 | 0.70 | UTRN (0.48) | LMNAKDM4ECYP1A2POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9196847-B2 | Sensitizing complexes, process for the preparation thereof, semiconductive inorganic/organic hybrid material comprising them, and photovoltaic cell comprising said material | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2015-11-24 | — | — | US | disclosed |
| US-20080276985-A1 | Sensitizing Complexes, Process For The Preparation Thereof, Semiconductive Inorganic/Organic Hybrid Material Comprising Them, And Photovoltaic Cell Comprising Said Material | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-11-13 | — | — | US | disclosed |