⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20346867 | 0.94 | ALDH1A1 (0.59) | — | |
| SCHEMBL13398683 | 0.92 | ALDH1A1 (0.64) | — | |
| SCHEMBL13398970 | 0.92 | ALDH1A1 (0.64) | — | |
| SCHEMBL11989150 | 0.92 | ALDH1A1 (0.64) | — | |
| SCHEMBL13398965 | 0.92 | ALDH1A1 (0.64) | — | |
| SCHEMBL15281652 | 0.92 | ALDH1A1 (0.64) | — | |
| SCHEMBL29026075 | 0.85 | ALDH1A1 (0.48) | — | |
| SCHEMBL180666 | 0.84 | — | — | |
| SCHEMBL988309 | 0.84 | — | — | |
| SCHEMBL160547 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-117534631-B | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-117534631-A | Phenylthiazole amine PI4KIII beta inhibitor, preparation method, pharmaceutical composition and application thereof | 南京市鸿舜医药科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20230285561-A1 | Targeting Microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2023-09-14 | — | — | US | disclosed |
| US-11642410-B2 | Targeting microbubbles | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-05-09 | — | — | US | disclosed |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9921477-B2 | Photoactivable nitrogen bases | BASE SE (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20160367669-A1 | TARGETING MICROBUBBLES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-12-22 | — | — | US | disclosed |
| US-8735609-B2 | Bryostatin analogues, synthetic methods and uses | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130123518-A1 | Bryostatin Analogues, Synthetic Methods and Uses | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-05-16 | — | — | US | disclosed |
| CN-1350458-A | Protease inhibitors | SMITHKLINE BEECHAM CORP (US) | 2002-05-22 | — | — | CN | disclosed |
| EP-1158986-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001095911-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |
| EP-1158986-A1 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000038687-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |
| US-5939428-A | ANTITUMOR AGENTS AND ANTIGROWTH AGENTS FOR CELLS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 1999-08-17 | — | — | US | disclosed |
| US-5354864-A | Antitumor agents | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-10-11 | — | — | US | disclosed |
| WO-1993023049-A1 | 3-(9-ACRIDINYLAMINO)-5-HYDROXYMETHYLANILINE DERIVATIVES AS ANTICANCER AGENTS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1993-11-25 | — | — | WO | disclosed |
| US-4127612-A | 19-Hydroxy PGE1 carbinol analogues | MILES LABORATORIES, INC. (US) | 1978-11-28 | — | — | US | disclosed |