Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5863528 | 0.90 | TSHR (0.64) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL1612393 | 0.90 | TSHR (0.51) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4415542 | 0.90 | TSHR (0.64) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2598194 | 0.90 | L3MBTL1 (0.59) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| Benzene SCHEMBL27561238 | 0.90 | L3MBTL1 (0.59) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11398188 | 0.90 | TDP1 (0.56) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9048708 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5469003 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9048699 | 0.89 | L3MBTL1 (0.58) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4406921 | 0.89 | TSHR (0.50) | TSHRSMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836061-A | Method for separating mixed acid | 绍兴贝斯美化工股份有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | claimed |
| CN-110483304-A | A kind of preparation method of 3- aminophthalic acid dimethyl ester | YANGZHOU POLYTECHNIC INST | 2019-11-22 | — | — | CN | claimed |
| CN-109999910-A | A kind of carbon material supported sulfonated polyaniline of biology and its application as catalyst | 扬州工业职业技术学院 | 2019-07-12 | — | — | CN | claimed |
| CN-109970568-A | A kind of green synthesis process of 3- aminophthalic acid dimethyl ester | 扬州工业职业技术学院 | 2019-07-05 | — | — | CN | claimed |
| US-10106550-B2 | Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2018-10-23 | — | — | US | claimed |
| US-20180134722-A1 | AZA-PHENALENE-3-KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND ITS APPLICATION AS PARP INHIBITOR | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2018-05-17 | — | — | US | claimed |
| EP-3305793-A1 | DERIVATIVE OF NITROGEN-DOPED PHENALENE-3-KETONE, PREPARATION METHOD THEREFOR AND APPLICATION OF DERIVATIVE USED AS PARP INHIBITOR | Suzhou Kangrun Pharmaceuticals, Inc. (CN) | 2018-04-11 | — | — | EP | claimed |
| CN-104876877-B | A kind of synthetic method of the carboxylate methyl ester of 2 ethoxybenzoimidazole 7 | 峨眉山宏昇药业股份有限公司 | 2018-03-09 | — | — | CN | claimed |
| CN-104945406-B | Derivative, its preparation method and its application as PARP inhibitor of that non-ketone of alkene 3 of azepine | 苏州康润医药有限公司 | 2017-10-10 | — | — | CN | claimed |
| CN-106631844-A | Preparation method of dimethyl 3-aminophthalate | 山东友帮生化科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104945406-A | Aza-phenalene-3-ketone derivative, preparation method thereof and application of aza-phenalene-3-ketone derivative as PARP inhibitor | SUZHOU KANGRUN PHARMACEUTICALS INC | 2015-09-30 | — | — | CN | claimed |
| CN-104876877-A | Synthesis method of 2-ethoxy benzimidazole-7-carboxylic acid methyl ester | EMEISHAN HONGSHENG PHARMACEUTICAL CO LTD | 2015-09-02 | — | — | CN | claimed |
| CN-100390152-C | Method for synthesizing 3-nitro or 3-amino phthalyl hydrazine | JIAN PAN (CN) | 2008-05-28 | — | — | CN | claimed |
| CN-1821230-A | Method for synthesizing 3-nitro or 3-amino phthalyl hydrazine | PAN JIAN (CN) | 2006-08-23 | — | — | CN | claimed |
| CN-116836061-A | Method for separating mixed acid | 绍兴贝斯美化工股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-109970568-B | Synthesis process of 3-amino dimethyl phthalate | 扬州工业职业技术学院 | 2022-09-02 | — | — | CN | disclosed |
| WO-1999054308-A1 | 5-AMINOINDENO(1,2-C)PYRAZOL-4-ONES AS ANTI-CANCER AND ANTI-PROLIFERATIVE AGENTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-10-28 | — | — | WO | disclosed |
| US-4374979-A | Regiospecific synthesis of anthracyclinone compounds such as daunomycinone | THE UNIVERSITY OF KANSAS ENDOWMENT ASSOCIATION (US) | 1983-02-22 | — | — | US | disclosed |
| EP-0063945-A1 | Process for the regiospecific synthesis of anthracyclinone compounds such as daunomycinone | THE UNIVERSITY OF KANSAS (US) | 1982-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134722-A1 | AZA-PHENALENE-3-KETONE DERIVATIVE, PREPARATION METHOD THEREOF, AND ITS APPLICATION AS PARP INHIBITOR | PARP1, PARP11, PARP3 | TSHR 4207/4885SMN1; SMN2 4340/4885KMT2A 111/4885 |
| US-10106550-B2 | Aza-phenalene-3-ketone derivative, preparation method thereof, and its application as PARP inhibitor | PARP1, PARP11, PARP3 | TSHR 4207/4885SMN1; SMN2 4340/4885KMT2A 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.