Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103519 | 0.90 | HTR4 (0.61) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5103071 | 0.90 | HTR4 (0.60) | HTR4KCNH2NPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL5096300 | 0.90 | HTR4 (0.60) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5110145 | 0.89 | HTR4 (0.64) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5110168 | 0.87 | HTR4 (0.67) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5099856 | 0.87 | HTR4 (0.67) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5096305 | 0.86 | HTR4 (0.66) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL5099866 | 0.85 | HTR4 (0.59) | HTR4KCNH2NPC1RAB9AGAA | |
| SCHEMBL8268953 | 0.79 | HTR4 (0.38) | HTR4KCNH2CYP3A4CCR1PARP1 | |
| SCHEMBL2209069 | 0.78 | HTR4 (0.81) | HTR4KCNH2RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407966-B2 | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE, INC. (US) | 2008-08-05 | — | — | US | claimed |
| US-20060079547-A1 | Thienopyridinone compounds and methods of treatment | NANOSHIFT, LLC | 2006-04-13 | — | — | US | claimed |
| US-7407966-B2 | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407966-B2 | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407966-B2 | Thienopyridinone compounds and methods of treatment | EPIX DELAWARE, INC. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20060079547-A1 | Thienopyridinone compounds and methods of treatment | NANOSHIFT, LLC | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079547-A1 | Thienopyridinone compounds and methods of treatment | HRH4, HRH2, HTR4 | HTR4 3/4885KCNH2 3236/4885CYP3A4 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.