Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101560 | 1.00 | GPR183 (0.41) | GPR183GSK3BKCNH2HSD11B1GCGR | |
| SCHEMBL5094862 | 0.87 | GPR183 (0.42) | GPR183GSK3BKCNH2GCGRRAB9A | |
| SCHEMBL5094868 | 0.87 | GPR183 (0.42) | GPR183GSK3BKCNH2GCGRRAB9A | |
| SCHEMBL5101761 | 0.87 | GPR183 (0.38) | GPR183GSK3BKCNH2SMN1; SMN2 | |
| SCHEMBL5101764 | 0.87 | GPR183 (0.38) | GPR183GSK3BKCNH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5102044 | 0.86 | KCNH2 (0.38) | GPR183GSK3BKCNH2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5102040 | 0.86 | KCNH2 (0.38) | GPR183GSK3BKCNH2SMN1; SMN2 | |
| SCHEMBL5107832 | 0.86 | GPR183 (0.36) | GPR183GSK3BKCNH2HSD11B1GCGR | |
| SCHEMBL5094916 | 0.85 | GSK3B (0.44) | GSK3BGCGRRAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL5094854 | 0.81 | GSK3B (0.41) | GSK3BGCGRRAB9ASMN1; SMN2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314877-B2 | Benzofuran derivative | KOWA CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| US-20060189621-A1 | Benzofuran derivative | KOWA CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1602655-A1 | BENZOFURAN DERIVATIVE | Kowa Co., Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189621-A1 | Benzofuran derivative | TNF, TNFRSF1A, RELA | GPR183 1025/4885GSK3B 3567/4885KCNH2 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.