SCHEMBL510325

SCHEMBL510325

OC[C@H]1O[C@@H](c2nc3ncncc3s2)[C@H](O)[C@@H]1O

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 12/20 0.45
▸ ADA P00813 1/20 0.40
▸ PYGL P06737 3/20 0.39
▸ HIF1A Q16665 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1594082 1.00 SLC5A2 (0.45) SLC5A2ADAPYGLHIF1A
SCHEMBL30025957 1.00 SLC5A2 (0.45) SLC5A2ADAPYGLHIF1A
SCHEMBL7048838 0.73 P2RY2 (0.60) SLC5A2PYGL
SCHEMBL6395173 0.73 P2RY2 (0.60) SLC5A2PYGL
SCHEMBL937118 0.72 KDM4E (0.54) ADAPYGLHIF1A
SCHEMBL509237 0.72 KDM4E (0.54) ADAPYGLHIF1A
SCHEMBL5163143 0.72 KDM4E (0.54) ADAPYGLHIF1A
SCHEMBL6884830 0.72 KDM4E (0.54) ADAPYGLHIF1A
SCHEMBL6935273 0.72 KDM4E (0.54) ADAPYGLHIF1A
SCHEMBL8791673 0.72 KDM4E (0.54) ADAPYGLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8211863-B2 Administration of TLR7 ligands and prodrugs thereof for treatment of infection by hepatitis C virus ANADYS PHARMACEUTICALS, INC. (US) 2012-07-03 — — US disclosed
US-20120028999-A1 ADMINISTRATION OF TLR7 LIGANDS AND PRODRUGS THEREOF FOR TREATMENT OF INFECTION BY HEPATITIS C VIRUS ANADYS PHARMACEUTICALS, INC. (US) 2012-02-02 — — US disclosed
EP-1603476-A2 METHOD OF TATTOO REMOVAL 3M Innovative Properties Company (US) 2005-12-14 — — EP disclosed
EP-1601365-A2 PROPHYLACTIC TREATMENT OF UV-INDUCED EPIDERMAL NEOPLASIA 3M Innovative Properties Company (US) 2005-12-07 — — EP disclosed
WO-2004080292-A2 METHOD OF TATTOO REMOVAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-09-23 — — WO disclosed
WO-2004078138-A2 PROPHYLACTIC TREATMENT OF UV-INDUCED EPIDERMAL NEOPLASIA 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-09-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120028999-A1 ADMINISTRATION OF TLR7 LIGANDS AND PRODRUGS THEREOF FOR TREATMENT OF INFECTION BY HEPATITIS C VIRUS TLR7, TLR3, TLR9 SLC5A2 2629/4885ADA 471/4885PYGL 146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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