Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | PYGL | P06737 | 9/20 | 0.48 |
| ▸ | ADA | P00813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2914679 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5182343 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL5163143 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL3727546 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL937118 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8791673 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6440905 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL509237 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884830 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL6884009 | 1.00 | KDM4E (0.54) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118019526-A | Methods for preparing lipid nanoparticle compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-118019527-A | Method for preparing lipid nanoparticle compositions | 摩登纳特斯有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-116348147-A | Compositions for delivery of payload molecules to airway epithelium | 摩登纳特斯有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-115867311-A | Polynucleotides comprising antigen cargo | 纳特科瑞克股份有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115677807-A | 6-position alpha-hydroxyalkylated purine compounds and methods for modification thereof | 鲁东大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-113164555-A | Compositions and methods for treating smooth muscle dysfunction | 尤偌万科学有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-110662770-A | Bispecific antibodies that bind factor IX and factor X | 比奥维拉迪维治疗股份有限公司 | 2020-01-07 | — | — | CN | disclosed |
| EP-0651759-B1 | NOVEL 2'-O-ALKYL NUCLEOSIDES AND PHOSPHORAMIDITES PROCESSES FOR THE PREPARATION AND USES THEREOF | ISIS PHARMACEUTICALS INC (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2001071043-A1 | LOOP PROBE HYBRIDIZATION ASSAY FOR POLYNUCLEOTIDE ANALYSIS | QUANTUM DOT CORPORATION (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0824345-A4 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORP (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0886641-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0824345-A1 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORPORATION (US) | 1998-02-25 | — | — | EP | disclosed |
| WO-1997026270-A2 | SYNTHESIS OF METHOXY NUCLEOSIDES AND ENZYMATIC NUCLEIC ACID MOLECULES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1997-07-24 | — | — | WO | disclosed |
| WO-1996033703-A2 | S-ADENOSYL METHIONINE REGULATION OF METABOLIC PATHWAYS AND ITS USE IN DIAGNOSIS AND THERAPY | ORIDIGM CORPORATION (US) | 1996-10-31 | — | — | WO | disclosed |