SCHEMBL5103371

SCHEMBL5103371

c1ccc(N(c2ccccc2)c2cccc(-c3cccc(-c4ccccn4)c3)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.42
KDM4E B2RXH2 5/20 0.42
LMNA P02545 4/20 0.42
TP53 P04637 3/20 0.42
CCR1 P32246 3/20 0.42
CCR5 P51681 3/20 0.42
CCR8 P51685 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALPL P05186 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
RAB9A P51151 4/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5108872 0.90 RAB9A (0.39) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL30109153 0.82 CYP2A6 (0.46) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL16484524 0.82 CYP2A6 (0.46) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL5115970 0.82 CYP2A6 (0.46) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL12150676 0.82 TLR4 (0.38) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL24269007 0.81 TRPV1 (0.39) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL28432843 0.81 GRM5 (0.43) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL13231354 0.81 RAB9A (0.38) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL5102763 0.81 CYP2A6 (0.44) SMN1; SMN2KDM4ELMNATP53CCR1
SCHEMBL5115890 0.80 MEN1 (0.59) SMN1; SMN2KDM4ELMNATP53CCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1683804-B1 PLATINUM COMPLEX AND LUMINESCENT ELEMENT TAKASAGO PERFUMERY CO LTD (JP) 2013-07-31 EP disclosed
EP-1683804-B1 PLATINUM COMPLEX AND LUMINESCENT ELEMENT TAKASAGO PERFUMERY CO LTD (JP) 2013-07-31 EP disclosed
CN-100445294-C Platinum complex and luminescent element TAKASAGO PERFUMERY CO LTD (JP) 2008-12-24 CN disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-7442797-B2 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-10-28 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
US-20070103060-A1 Platinum complex and light emitting device TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-05-10 US disclosed
EP-1683804-A2 PLATINUM COMPLEX AND LUMINESCENT ELEMENT Takasago International Corporation (JP) 2006-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070103060-A1 Platinum complex and light emitting device UBE2D3, PCID2, CCND2 SMN1; SMN2 2759/4885KDM4E 3127/4885LMNA 3397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.