Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | APEX1 | P27695 | 3/20 | 0.67 |
| ▸ | APAF1 | O14727 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.67 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | PPARG | P37231 | 2/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.66 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | ALB | P02768 | 1/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105813 | 1.00 | NR1I2 (0.69) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5098950 | 0.92 | NR1I2 (0.75) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5096575 | 0.91 | TDP1 (0.77) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5099406 | 0.90 | NR1I2 (0.74) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5099388 | 0.90 | NR1I2 (0.74) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5105299 | 0.89 | NR1I2 (0.68) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL7035667 | 0.89 | NR1I2 (0.68) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL7148776 | 0.88 | NR1I2 (0.66) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL5098930 | 0.88 | NR1I2 (0.66) | NR1I2HTR2CTDP1APEX1APAF1 | |
| SCHEMBL9481831 | 0.88 | TDP1 (0.83) | NR1I2HTR2CTDP1APEX1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317101-B2 | Antibacterial cephalosporins | SANDOZ GMBH (AT) | 2008-01-08 | — | — | US | disclosed |
| EP-1221446-B1 | Antibacterial cephalosporins | SANDOZ AG (CH) | 2005-04-06 | — | — | EP | disclosed |
| US-20030191105-A1 | Antibacterial cephalosporins | NABRIVA THERAPEUTICS AG (AT) | 2003-10-09 | — | — | US | disclosed |
| US-6531465-B1 | 7-acylamino-3-(imino)methyl cephalosporins; 7-[[(5-Amino-1,2,4-thiadiazol-3-yl)-(Z)-(fluormethoxyimino)acetyl]amino]-3-[[(piperazinoiminomethyl)hydrazono]methyl]-3-cephem-4-carboxylic acid; imination of 3-methyl derivative; acylation at the 7-amino; 1-[hydrazino(methylimino)methyl]piperazine intermediate | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-03-11 | — | — | US | disclosed |
| EP-0824535-B1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GMBH (AT) | 2003-02-26 | — | — | EP | disclosed |
| EP-1221446-A1 | Antibacterial cephalosporins | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2002-07-10 | — | — | EP | disclosed |
| EP-0824535-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1998-02-25 | — | — | EP | disclosed |
| WO-1996035692-A1 | ANTIBACTERIAL CEPHALOSPORINS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1996-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191105-A1 | Antibacterial cephalosporins | MRPL21, CIAPIN1, CSDE1 | NR1I2 410/4885HTR2C 4093/4885TDP1 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.