Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.66 |
| ▸ | HTR2C | P28335 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | PPARG | P37231 | 2/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.64 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.64 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.64 |
| ▸ | ALB | P02768 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | APEX1 | P27695 | 3/20 | 0.63 |
| ▸ | APAF1 | O14727 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.63 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.62 |
| ▸ | MMP2 | P08253 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098930 | 1.00 | NR1I2 (0.66) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5105299 | 0.93 | NR1I2 (0.68) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL7035667 | 0.90 | NR1I2 (0.68) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5098950 | 0.89 | NR1I2 (0.75) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5099388 | 0.88 | NR1I2 (0.74) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5099406 | 0.88 | NR1I2 (0.74) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5099296 | 0.88 | PTGS1 (0.70) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL7148779 | 0.88 | PTGS1 (0.70) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5099292 | 0.88 | PTGS1 (0.70) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL5105813 | 0.88 | NR1I2 (0.69) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6531465-B1 | 7-acylamino-3-(imino)methyl cephalosporins; 7-[[(5-Amino-1,2,4-thiadiazol-3-yl)-(Z)-(fluormethoxyimino)acetyl]amino]-3-[[(piperazinoiminomethyl)hydrazono]methyl]-3-cephem-4-carboxylic acid; imination of 3-methyl derivative; acylation at the 7-amino; 1-[hydrazino(methylimino)methyl]piperazine intermediate | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2003-03-11 | — | — | US | disclosed |