Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4768498 | 0.90 | CCR5 (0.76) | CCR5 | |
| SCHEMBL4777969 | 0.88 | CCR5 (0.61) | CCR5 | |
| SCHEMBL4777213 | 0.85 | CCR5 (0.80) | CCR5 | |
| SCHEMBL4777087 | 0.83 | CCR5 (0.80) | CCR5 | |
| SCHEMBL4775117 | 0.83 | CCR5 (0.65) | CCR5 | |
| SCHEMBL4778136 | 0.82 | CCR5 (0.60) | CCR5 | |
| SCHEMBL4775221 | 0.81 | CCR5 (0.71) | CCR5 | |
| SCHEMBL4777129 | 0.81 | CCR5 (0.77) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4777669 | 0.81 | CCR5 (0.62) | CCR5 | |
| Trifluoroacetic Acid SCHEMBL4771541 | 0.81 | CCR5 (0.67) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348324-B2 | Cyclic amine compounds as CCR5 antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-03-25 | — | — | US | disclosed |