SCHEMBL51066

SCHEMBL51066

CCCCc1ccc(O)c(Cc2cc(CCCC)ccc2O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.55
HPGD P15428 1/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
RAB9A P51151 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
BACE1 P56817 1/20 0.53
KAT8 Q9H7Z6 2/20 0.50
IGF1R P08069 2/20 0.50
ALOX15 P16050 2/20 0.50
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50
ALOX5 P09917 1/20 0.47
IAPP P10997 1/20 0.47
TYR P14679 1/20 0.47
PPARA Q07869 1/20 0.46
SKP2 Q13309 1/20 0.46
ESR1 P03372 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4649416 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL3703400 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL30294037 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL3691456 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL3129115 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL836353 0.93 KAT8 (0.59) HTTBACE1KAT8IGF1RALOX15
SCHEMBL1024663 0.90 HPGD (0.57) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL11265415 0.90 ESR1 (0.53) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1021131 0.89 ALOX5 (0.60) NPC1HPGDMAPK1HTTRAB9A
SCHEMBL1023618 0.89 BACE1 (0.68) NPC1HPGDMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181853-B1 Thermosensitive recording medium JUJO PAPER CO LTD (JP) 2015-09-23 EP disclosed
US-8492308-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2013-07-23 US disclosed
US-8202821-B2 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD (JP) 2012-06-19 US disclosed
US-8129307-B2 Thermosensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2012-03-06 US disclosed
US-20110269622-A1 THERMOSENSITIVE RECORDING MEDIUM NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2011-11-03 US disclosed
US-20110130281-A1 THERMOSENSITIVE RECORDING MEDIUM API CORPORATION 2011-06-02 US disclosed
EP-2112001-B1 THERMOSENSITIVE RECORDING MEDIUM JUJO PAPER CO LTD (JP) 2011-05-11 EP disclosed
EP-2261045-A1 HEAT-SENSITIVE RECORDING MEDIUM Nippon Paper Industries Co., Ltd. (JP) 2010-12-15 EP disclosed
EP-2200826-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE Eastman Kodak Company (US) 2010-06-30 EP disclosed
EP-2181853-A1 THERMAL RECORDING MATERIAL Nippon Paper Industries Co., Ltd. (JP) 2010-05-05 EP disclosed
US-20100099557-A1 Thermosensitive Recording Medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2010-04-22 US disclosed
WO-2010033182-A1 ON-PRESS DEVELOPABLE IMAGEABLE ELEMENTS EASTMAN KODAK COMPANY (US) 2010-03-25 WO disclosed
US-20090280980-A1 Thermal recording material NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2009-11-12 US disclosed
EP-2072274-A1 HEAT-SENSITIVE RECORDING MATERIAL Nippon Paper Industries CO., LTD. (JP) 2009-06-24 EP disclosed
WO-2009054904-A1 NEGATIVE-WORKING IMAGEABLE ELEMENTS AND METHODS OF USE EASTMAN KODAK COMPANY (US) 2009-04-30 WO disclosed