Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5107130 | 1.00 | LMNA (0.61) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL30172716 | 1.00 | LMNA (0.61) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL5107133 | 1.00 | LMNA (0.61) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL28639572 | 0.91 | LMNA (0.52) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL6055088 | 0.91 | LMNA (0.52) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL5907398 | 0.87 | LMNA (0.54) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL593087 | 0.85 | LMNA (0.52) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL3929484 | 0.85 | LMNA (0.52) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL2990957 | 0.85 | TSHR (0.65) | LMNATSHRPDE2ATRPA1AOC3 | |
| SCHEMBL30295406 | 0.85 | TSHR (0.65) | LMNATSHRPDE2ATRPA1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465838-B2 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | CIBA SPECIALTY CHEMICAL CORP. (US) | 2008-12-16 | — | — | US | disclosed |
| US-20060030737-A1 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | CIBA SPECIALTY CHEMICALS CORP. | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030737-A1 | Chiral diols, their manufacture and ligands and catalysts derived therefrom | B2M, CYP4F11, CYP2F1 | LMNA 3056/4885TSHR 1755/4885PDE2A 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.