Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491870 | 0.79 | HRH3 (0.56) | HRH3BCHEACHEALDH1A1KMT2A | |
| SCHEMBL27785772 | 0.78 | HRH3 (0.59) | HRH3BCHEACHEALDH1A1KMT2A | |
| SCHEMBL27785816 | 0.74 | HRH3 (0.54) | HRH3BCHEACHEALDH1A1KMT2A | |
| SCHEMBL12741310 | 0.73 | MAOB (0.51) | HRH3MAOB | |
| SCHEMBL14287631 | 0.73 | KDM4E (0.50) | HRH3ALDH1A1KDM4E | |
| SCHEMBL14287780 | 0.72 | HRH3 (0.56) | HRH3BCHEACHEALDH1A1KMT2A | |
| SCHEMBL5107279 | 0.72 | HRH3 (0.56) | HRH3BCHEACHEALDH1A1KMT2A | |
| SCHEMBL9827594 | 0.71 | EBP (0.59) | HRH3ALDH1A1KMT2AKDM4ECHRM2 | |
| SCHEMBL491797 | 0.70 | L3MBTL1 (0.69) | HRH3BCHEACHEMAOB | |
| SCHEMBL5418369 | 0.70 | TP53 (0.64) | HRH3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314937-B2 | Non-imidazole aryl alkylamines compounds as histamine H3 receptor antagonists, preparation and therapeutic uses | ELI LILLY AND COMPANY (US) | 2008-01-01 | — | — | US | disclosed |