SCHEMBL5107809

SCHEMBL5107809

CCCN1C(=O)Cc2cc(N3CC(CN)OC3=O)ccc21

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.47
GRM2 Q14416 14/20 0.43
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5107804 1.00 F10 (0.47) F10GRM2MAOB
SCHEMBL5998598 0.91 F10 (0.49) F10GRM2MAOB
SCHEMBL5115309 0.90 F10 (0.48) F10GRM2MAOB
SCHEMBL5115299 0.90 F10 (0.48) F10GRM2MAOB
Hydrochloric Acid SCHEMBL5506711 0.90 F10 (0.48) F10GRM2MAOB
Hydrochloric Acid SCHEMBL5506708 0.90 F10 (0.48) F10GRM2MAOB
SCHEMBL5113182 0.85 F10 (0.47) F10GRM2MAOB
SCHEMBL5113186 0.85 F10 (0.47) F10GRM2MAOB
SCHEMBL5507922 0.84 MAOA (0.47) F10GRM2MAOB
SCHEMBL5507911 0.84 MAOA (0.47) F10GRM2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents PFIZER INC 2008-10-23 US disclosed
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent JOSYULA VARA PRASAD V N 2006-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060229348-A1 Oxindole oxazolidinone as antibacterial agent OXA1L, MRPL21, RPS27L F10 1720/4885GRM2 3560/4885MAOB 1778/4885
US-20080262056-A1 Oxindole Oxazolidinones as Antibacterial Agents OXA1L, OXSR1, OXER1 F10 784/4885GRM2 3782/4885MAOB 412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.