Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.34 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.32 |
| ▸ | GRM5 | P41594 | 4/20 | 0.32 |
| ▸ | XDH | P47989 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108864 | 0.88 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5113119 | 0.87 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5108620 | 0.86 | SLC29A1 (0.40) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5109214 | 0.83 | ALDH1A1 (0.34) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL5108344 | 0.78 | PI4KA (0.49) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5110970 | 0.77 | KDR (0.47) | PTK2PTK2B | |
| SCHEMBL20201240 | 0.77 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5108348 | 0.76 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBGPR119 | |
| SCHEMBL5111659 | 0.75 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBEGFR | |
| SCHEMBL5118492 | 0.74 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609656-B2 | Heteroarylphenylurea derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20080119466-A1 | Heteroarylphenylurea Derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1724258-A1 | HETEROARYLPHENYLUREA DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119466-A1 | Heteroarylphenylurea Derivative | CHRM1, CBR3, CHRM2 | PI4KA 4459/4885PI4K2B 3789/4885PI4K2A 4318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.