Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 8/20 | 0.55 |
| ▸ | ACHE | P22303 | 8/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007931 | 1.00 | BCHE (0.55) | BCHEACHEKDRTP53BP1NAMPT | |
| SCHEMBL13811516 | 0.89 | BCHE (0.56) | BCHEACHETP53BP1MCHR1HTR2A | |
| SCHEMBL13683770 | 0.84 | GRM4 (0.66) | KDRGRM4MCHR1 | |
| SCHEMBL13683431 | 0.78 | KDR (0.52) | KDRGRM4MCHR1HTR2AHTR2C | |
| SCHEMBL4015144 | 0.78 | BCHE (0.48) | BCHEACHEKDRNAMPTMCHR1 | |
| SCHEMBL4006802 | 0.78 | KDR (0.50) | BCHEACHEKDRMCHR1 | |
| SCHEMBL4006797 | 0.78 | KDR (0.50) | BCHEACHEKDRMCHR1 | |
| SCHEMBL3865174 | 0.78 | KDR (0.62) | BCHEACHEKDRMCHR1HTR2A | |
| Hydrochloric Acid SCHEMBL3866249 | 0.77 | KDR (0.51) | KDRGRM4MCHR1HTR2AHTR2C | |
| SCHEMBL14209512 | 0.76 | KDR (0.60) | KDRMCHR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | MCHR2, MCHR1, NPY1R | BCHE 995/4885ACHE 2784/4885KDR 4188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.