Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.48 |
| ▸ | ACHE | P22303 | 7/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4015413 | 0.79 | KDR (0.51) | KDRHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4010154 | 0.78 | KDR (0.53) | KDRHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL4007931 | 0.78 | BCHE (0.55) | BCHEACHEKDRNAMPTHTR2A | |
| SCHEMBL5108944 | 0.78 | BCHE (0.55) | BCHEACHEKDRNAMPTHTR2A | |
| SCHEMBL3865174 | 0.77 | KDR (0.62) | BCHEACHEKDRHTTRORC | |
| SCHEMBL4006797 | 0.77 | KDR (0.50) | BCHEACHEKDRALDH1A1MCHR1 | |
| SCHEMBL4006802 | 0.77 | KDR (0.50) | BCHEACHEKDRALDH1A1MCHR1 | |
| SCHEMBL4011687 | 0.76 | KDM4E (0.46) | KDRHDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL14209957 | 0.73 | BCHE (0.49) | BCHEACHEKDRALDH1A1MCHR1 | |
| SCHEMBL14209512 | 0.73 | KDR (0.60) | KDRHDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558567-B1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-06-24 | — | — | EP | claimed |